| Rotation | PICO/Mini-CAT | Question |
| Rotation 2 – Emergency Medicine | PICO 1 | In adults with uncomplicated skin abscess treated with incision and drainage, does adjunctive antibiotic therapy compared with incision and drainage alone improve cure rates and reduce recurrence? |
| Rotation 2 – Emergency Medicine | PICO 2 | In adults with elevated serum lactate but no confirmed infection, does early empiric antibiotic administration compared with observation or targeted therapy improve clinical outcomes? |
| Rotation 2 – Emergency Medicine | PICO 3 | In hemodynamically stable adults with recent onset atrial fibrillation, does early rhythm control compared with rate control alone improve symptom resolution? |
| Rotation 3 – Family Medicine | PICO 4 | In patients with Type 2 diabetes without established cardiovascular disease, does adding SGLT2 inhibitors or GLP-1 receptor agonists compared with standard therapy reduce future cardiovascular events? |
| Rotation 3 – Family Medicine | PICO 5 | In adults over age 45 undergoing colorectal cancer screening, does combining stool-based testing with colonoscopy compared with colonoscopy alone improve detection of colorectal cancer? |
| Rotation 3 – Family Medicine | PICO 6 | In adults above 65 years old, does getting the influenza vaccine compared to not getting the vaccine reduce the risk of contracting pneumonia during the cold season? |
| Rotation 4 – Internal Medicine | Mini-CAT | In adults with Hashimoto’s disease already treated with levothyroxine, does the addition of T3 (liothyronine) lead to reduced fatigue and improved quality of life compared to continuing levothyroxine monotherapy alone? |
| Rotation 5 – Psychiatry | PICO 7 | |
| Rotation 5 – Psychiatry | PICO 8 | |
| Rotation 5 – Psychiatry | PICO 9 | |
| Rotation 6 – Pediatrics | Mini-CAT |
